ABSTRACT
The liposome prepared by ethanol injection method by using Phosphatidylcholine and cholesterol at 10:10 ratio shown good % Entrapment efficiency and In-vitro drug release study. Optimized formulations were subjected to stability studies at two different temperatures for up to 45 day. No significant changes in drug entrapment efficiency and mean particle size were observed during the course of stability study for formulations stored at 4-8ºC but there was a significant decrease in drug entrapment efficiency for liposome stored at room temperature after 15, 30 and 45 days and the mean particle size were increased at room temperature after 15, 30 and 45 days.