E-ISSN 2229-4619
  International Journal of Pharmaceutical Studies and Research
                                                                     -An Open Access Peer Reviewed e-Journal

 
 

PREPARATION AND CHARACTERIZATION OF SERRATIOPEPTIDASE CONTAINING MICROSPHERES

Authors: J.S. Dua, Prof. A. C. Rana, Dr. A. K. Bhandari
  IJPSR/Volume IV/ Issue I/ January-March, 2013/1-3
 

ABSTRACT
In the study we formulated the serratiopeptidase loaded cholic acid conjugated and unconjugated chitosan mucoadhesive microspheres. It was observed that the conjugated microspheres show better permeation rate than unconjugated microspheres. Moreover the permeation enhancer increased the % cumulative drug permeation through the mucosal membrane from 69.37 % to 74.39 % for unconjugated microspheres and conjugated microspheres respectively.